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Golden Seal is used traditionally to:
- Help maintain healthy mucous membranes*
- Relieve mild temporary digestive discomfort*
- Support healthy mucous membranes in the respiratory and gastrointestinal tracts*
- Work as a tonic to benefit the entire body*
- Stimulate digestion*
- Support liver function*
Golden Seal 500mg tablets contain alkaloids (especially hydrastine and berberine) and other phytochemicals.
Golden Seal Quality Story

Golden Seal (Hydrastis canadensis) is an endangered herb and as a result is very expensive and often substituted with other herbs.
The substituted herbs usually contain the substance berberine which provides the yellow color, but they do not contain hydrastine which is unique to Golden Seal. Only HPLC enables this differentiation to be made. MediHerb only buys cultivated Golden Seal to ensure long term sustainability of the herb. MediHerb tests each batch of Golden Seal raw material and finished product to ensure the claimed levels of hydrastine and berberine are present. Using HPLC, MediHerb is able to clearly differentiate true Golden Seal from other berberine-containing herbs. The table demonstrates the difference between the various berberine-containing species. The top trace is an example of substitution where a professional product being sold in Australia as Indian Golden Seal matched the trace of Coptis chinensis.
Suggested Use:
1 tablet 2 - 3 times daily, or as directed.
Caution: Contraindicated in pregnancy, lactation and patients with high blood pressure. For other contraindications and cautions consult your health care professional. Keep out of reach of children. Store in a cool, dry place out of direct sunlight.
Nutrients & Ingredients
Each Serving Size (1 Tablet) contains: Calcium 97 mg, Golden Seal root & rhizome 4:1 extract 125 mg (from Hydrastis canadensis root and rhizome 500 mg). Other Ingredients: Dibasic calcium phosphate dihydrate, microcrystalline cellulose, silicon dioxide, magnesium stearate, hypromellose, sodium starch glycolate.
For other contraindications and cautions, please refer to the Potential Herb-Drug Interactions Chart.
Please consult the actual product label for the most accurate product information.
*These statements have not been evaluated by the Food and Drug Administration. These products are not intended to diagnose, treat, cure, or prevent any disease.
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